In Myst V: When you change the resolution on a Mac, 1280×1024 and 800×600 stretch off the screen. If you close Myst V and relaunch it, the resolutions fit the screen fine.

In URU: In the 1280×1024 and 1600×1200 fullscreen resolutions there is an invisible mouse cursor border in the window. In fullscreen, you can’t mouse over the bottom of the screen to open the options menu/quit the game or use your linking book.
If you play URU: Complete Chronicles windowed, the 1280×1024 and 1600×1200 resolutions work as expected.